Detail
Chemical name: Methoxypoly(ethylene glycol) ditetradecylacetamide
2-[(polyethylene glycol)-2000]-N,N ditetradecylacetamide;
Appearance: White to Yellow Solid
Solubility: DMF: 10 mg/ml;
DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml;
DMSO: Slightly Soluble;
Ethanol: 1 mg/ml
Description: ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine that contains the active ingredient tozinameran.
Specifications:95% HPLC (ELSD)
Use:
Methoxypoly(ethylene glycol) ditetradecylacetamide can be used in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.
